Areas of Interest
LIVFRESH Dental Gel toothpaste
is already approved in EU
for Prevention & Treatment of Gingivitis & Periodontitis
FEATURED IN
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PLAQUE CONTROL
We have the first breakthrough in the dental industry since the introduction of fluoride in 1914.
LIVFRESH Dental Gel toothpaste is clinically proven to remove plaque 250% BETTER than a market leader.
All ingredients are edible and contain ZERO abrasives, antimicrobials, parabens, gluten, sugar, triclosan, & SLS.
LIVFRESH is commercially available in USA.
Dental get Tubes sold
# of Customers
5-Star Reviews
PERIODONTITIS
Periodontitis is serious gum disease with no current treatment. Gingivitis leads to periodontitis, which results in loss of teeth, significant discomfort/pain, and substantial decrease in quality of life. Periodontitis has been linked to dementia, Alzheimer’s and cardiac disease.
Prevalance
64M
PATIENTS IN THE US
Clinical Stage
PHASE 2
SCHEDULED 2023
![tooth-image-block tooth-image-block](https://livionex.com/wp-content/uploads/2023/01/tooth-image-block.png)
Increasing prevalence due to the aging population and the lack of availability of effective home care. According to the CDC, at least 47% of all US adults above 30 years, suffer from periodontitis.
Current standard of care are in-office treatments to slow down progression of periodontitis which can be painful, time-intensive, and expensive. Baseline treatments include scaling and root planing, and professional cleanings every 3 months. Surgery is suggested for advanced cases.
LIVFRESH Dental Gel toothpaste
Possible first affordable at-home treatment
![checkmark](https://livionex.wpengine.com/wp-content/uploads/2022/12/checkmark.png)
Double-Blind Study Shows Reduction of Pocket Depths
Pocket Depth > 4 mm are a marker for periodontitis. In the double-blind study, the LIVFRESH group showed significant reductions in diseased pocket depths, gum inflammation, gum bleeding and dental plaque.
![checkmark](https://livionex.wpengine.com/wp-content/uploads/2022/12/checkmark.png)
Ready to launch FDA Phase 2 study
Approval would make LIVFRESH the first affordable, at-home treatment for severe gum disease in USA
LIVFRESH launching anti-gingivitis toothpaste
in 2024
Relative Improvements Shown In A Double-Blind Study
![gingivitis graph_v2 gingivitis graph](https://livionex.wpengine.com/wp-content/uploads/2022/12/gingivitis-graph_v2.png)
SOURCE: PMID 35980316
30 subjects per arm with a 3-month study duration. Control is an ADA approved toothpaste containing sodium fluoride.
![livfresh](https://livionex.wpengine.com/wp-content/uploads/2022/12/tube-icon.png)
Livionex is launching an anti-plaque anti-gingivitis toothpaste in 2024
![monograph icon](https://livionex.wpengine.com/wp-content/uploads/2022/12/monograph-icon.png)
LivFresh Stannous Fluoride will be FDA Monograph compliant
![stock icon](https://livionex.wpengine.com/wp-content/uploads/2022/12/stock-icon.png)
2-5X more effective than ADA approved toothpaste